ACID NEUTRALIZING CAPACITY AND ANTIMICROBIAL POTENTIAL OF SELECTED SOLVENT EXTRACT FROM VARIOUS INDIGENOUS PLANTS

Medicinal plants have been representing a rich source of antimicrobial agent as well can be used antacid in various ayurvedic preparations. Hence the present study was undertaken to evaluate antibacterial potential and properties selected six plant extracts. The extracts such Methanolic Cassia tora (MECT), Pithecellobium dulce (MEPD), Chloroform Butea monosperma (CEBM), Butanolic Pongamia pinnata (BEPP), Water Tephrosia purpurea (WETP), Mucuna pruriens (MEMP) were for study. neutralization capacity vitro performed using titration method Fordtran’s model. activity by disc diffusion minimum inhibitory concentration determined broth dilution method. consumed volumes artificial gastric juices titrate pH 3.0 water, Sodium bicarbonate, MECT, MEPD, CEBM, BEPP, WETP MEMP solutions found 1.3±0.02, 34.22±0.59*, 8.26±0.08*, 10.58±0.09*, 9.6±0.1*, 7.35±0.05, 9.36±0.09* 9.88±0.06* respectively. highest extract has shown MECT 25.00 mm diameter zone inhibition against E. coli at 250 μg/disc followed 24.00 P. aeruginosa μg/disc. Against Gram positive organism, MEPD possess 21.00 20.00 respectively M. Lutues 250μg/disc. MIC values range 50-500μg/ml tested organisms. acid neutralizing higher among all extract. gram-negative gram-positive bacteria.